Our vision
Ion channels are key players in many physiological processes and their function is tightly regulated. We aim to understand how ion channels work at the molecular level to meet extremely versatile cellular needs. In particular, we are interested in ligand-gated ion channels and their allosteric regulation. We use a combination of biochemical, biophysical, electrophysiological, and structural approaches to characterize fundamental channel properties and their functional states.
We are located in the Gotto-Hamilton Laboratory Suite in Whitney Pavilion at Weill Cornell Medicine and feature an international research team with diverse scientific backgrounds. Our lab participates in the Physiology, Biophysics, and Systems Biology (PBSB) and Biochemistry & Structural Biology, Cell & Developmental Biology, and Molecular Biology (BCMB) programs. Graduate students and postdoctoral scholars interested in our research and joining the lab are encouraged to contact Crina Nimigean via email.
